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Sharp liabilities list covered worst-case scenarios: source

February 29, 2016 by · Leave a Comment 

Sharp Corp's list of liabilities that prompted Taiwan's Foxconn to suspend signing a takeover deal was an unverified study of worst-case scenario risks, rather than liabilities requiring disclosure, a source briefed on the matter said. The list, sent to Foxconn on Wednesday, included previously undisclosed potential liabilities worth around 300 billion yen ($2.6 billion), prompting Foxconn founder and billionaire Terry Gou to hold off signing the estimated $5.8 billion deal, separate sources have said. Reuters was unable to ascertain why the list was sent to Foxconn, formally known as Hon Hai Precision Industry Co .

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Sharp liabilities list covered worst-case scenarios: source

United States sets out limits on its spying as part of new data pact with EU

February 27, 2016 by · Leave a Comment 

By Julia Fioretti BRUSSELS (Reuters) – The United States has set out limits to its use of data collected in bulk about European citizens after a new information-sharing pact was agreed this month, according to documents seen by Reuters. A clear explanation of what information could be used for — preventing its “indiscriminate” and “arbitrary” use — was a key condition of the new Privacy Shield framework that enables firms to easily transfer personal data to the United States. Under the deal, Washington agreed to create a specific new role within the State Department to deal with complaints and enquiries forwarded by EU data protection agencies.

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United States sets out limits on its spying as part of new data pact with EU

Apple calls FBI iPhone request ‘unprecedented’ in court filing

February 25, 2016 by · Leave a Comment 

Apple Inc on Thursday struck back in court against a U.S. government demand that it unlock an encrypted iPhone belonging to one of the San Bernardino shooters, arguing such a move would violate its free speech rights and override the will of Congress. The high-stakes fight between Apple and the government burst into the open last week when the U.S. Federal Bureau of Investigation obtained a court order requiring Apple to write new software and take other measures to disable passcode protection and allow access to shooter Rizwan Farook's iPhone. The clash has driven to the heart of a long-running debate over how much law enforcement and intelligence officials should be able to monitor digital communications.

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Apple calls FBI iPhone request ‘unprecedented’ in court filing

Solid support for Apple in iPhone encryption fight: poll

February 24, 2016 by · Leave a Comment 

By Jim Finkle BOSTON (Reuters) – Nearly half of Americans support Apple Inc's decision to oppose a federal court order demanding that it unlock a smartphone used by San Bernardino shooter Rizwan Farook, according to a national online Reuters/Ipsos poll. Forty-six percent of respondents said they agreed with Apple's position, 35 percent said they disagreed and 20 percent said they did not know, according to poll results released on Wednesday. Other questions in the poll showed that a majority of Americans do not want the government to have access to their phone and Internet communications, even if it is done in the name of stopping terror attacks.

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Solid support for Apple in iPhone encryption fight: poll

Google is shuttering Google Compare: Wall Street Journal

February 23, 2016 by · Leave a Comment 

(Reuters) – Google is shuttering Google Compare, its U.S. comparison-shopping site for auto insurance, credit cards and mortgages after one year, the Wall Street Journal reported on Monday, citing people familiar with the matter. The quick reversal is a setback to the Alphabet unit's efforts to use its enormous reach to provide consumers with niche shopping services and financial-services tools, the Journal said. (Reporting by Eric Beech in Washington; Editing by Sandra Maler)

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Google is shuttering Google Compare: Wall Street Journal

U.S., Apple ratchet up rhetoric in fight over encryption

February 20, 2016 by · Leave a Comment 

By Dustin Volz and Julia Edwards WASHINGTON (Reuters) – The U.S. Department of Justice filed a motion on Friday seeking to compel Apple Inc to comply with a judge's order to unlock the encrypted iPhone belonging to one of the San Bernardino shooters, portraying the tech giant's refusal as a “marketing strategy.” In response, a senior Apple executive, speaking with reporters on condition of anonymity, characterized the Justice Department's filing as an effort to argue its case in the media before the company has a chance to respond. The Federal Bureau of Investigation is seeking the tech company's help to access shooter Syed Rizwan Farook's phone by disabling some of its passcode protections. Another senior Apple executive said Congress is the right place for a debate over encryption, not a courtroom.

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U.S., Apple ratchet up rhetoric in fight over encryption

U.S., Apple ratchet up rhetoric in fight over encryption

February 20, 2016 by · Leave a Comment 

By Dustin Volz and Julia Edwards WASHINGTON (Reuters) – The U.S. Department of Justice filed a motion on Friday seeking to compel Apple Inc to comply with a judge's order to unlock the encrypted iPhone belonging to one of the San Bernardino shooters, portraying the tech giant's refusal as a “marketing strategy.” In response, a senior Apple executive, speaking with reporters on condition of anonymity, characterized the Justice Department's filing as an effort to argue its case in the media before the company has a chance to respond. The Federal Bureau of Investigation is seeking the tech company's help to access shooter Syed Rizwan Farook's phone by disabling some of its passcode protections. Another senior Apple executive said Congress is the right place for a debate over encryption, not a courtroom.

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U.S., Apple ratchet up rhetoric in fight over encryption

U.S. ramps up Apple fight with new filing in iPhone unlocking case

February 19, 2016 by · Leave a Comment 

By Dustin Volz and Julia Edwards WASHINGTON/LOS ANGELES (Reuters) – The U.S. Department of Justice filed a motion seeking to compel Apple Inc to comply with a judge's order for the company to unlock the encrypted iPhone belonging to one of the San Bernardino shooters, portraying the tech giant's refusal as a “marketing strategy.” The filing escalated a showdown between the Obama administration and Silicon Valley over security and privacy that ignited earlier this week. The Federal Bureau of Investigation is seeking the tech giant's help to access the shooter's phone by disabling some of its passcode protections. Apple did not immediately respond to a request for comment.

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U.S. ramps up Apple fight with new filing in iPhone unlocking case

Therapeutic Applications of Oligonucleotides for Medicine-based Purposes

February 19, 2016 by · Leave a Comment 

In the coming years, oligonucleotides will play a large role in the therapeutics community.

Oligonucleotides are now an actively investigated therapeutic applicant in clinical trials. Researchers have been expressing cautious optimism on the positive effects that these oligos have on minimizing or curing genetically-deformed diseases.

Oligos and their chemically modified clones are being routinely researched to control the expression of relevant genes and dedicate them to therapeutic purposes. There has been optimistic belief that oligonucleotide therapy will succeed in the coming years as a medical agent for mutated diseases – the most common being cancer.

Biological Pathways

The fundamental events of the involving biological pathways have been generally understood to the point where chemical modifications can now be implemented in research strategies – such as the potency of therapeutic trials for oligonucleotides.

For oligonucleotide-based therapies, there are several classes of oligonucleotides that are used to control gene expression. Researchers are specifically emphasizing antisense oligos due to their modification strategies.

The biological pathways of oligonucleotides are a foundation for driving innovative strategies for optimal therapy. By combining the current advances, there can be a better understanding of the chemical “know-how’s”, which are essentially one of the keys to advancement within this field.

Obstacles

Oligonucleotide therapeutics does have certain impediments that include: low efficiency, poor extra- and intracellular stability, and immunostimulation. However, the recent development of oligonucleotide chemical modifications allows there to be less limiting features of both RNA and DNA polymers. These analogs allow for flexibility, which allows specific alterations to be made if necessary – in regards to the inherent properties of oligonucleotides that affect its’ biological potency.


 

The Midland Certified Reagent Company is an established supplier of oligonucleotides. Visit them online to order a modified oligo for your research purposes today.

Uber losing $1 billion a year to compete in China

February 18, 2016 by · Leave a Comment 

Uber Technologies Inc is burning through more than a billion dollars a year in China as it wages a fierce price war against local rival Didi Kuaidi, its chief executive said. The company's Chinese business boosted its valuation last month to more than $8 billion after raising more than $1 billion in its latest funding round, but the U.S. ride-hailing app is not yet profitable in mainland China because of the intense competition. “We're profitable in the USA, but we're losing over $1 billion a year in China,” Uber CEO Travis Kalanick told Canadian technology platform Betakit.

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Uber losing $1 billion a year to compete in China

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